Twelve-hourly dosage schedule for oral and intravenous metronidazole.

Paired samples of blood were examined from 48 patients undergoing major surgery who were receiving metronidazole at a 12-hourly dosage interval, as part of a regimen for prophylaxis or therapy. Twenty-five patients were given 400 mg metronidazole orally twice a day and 23 received 500 mg metronidazo... View More