Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function

Tang, Wenbo; Kowgier, Matthew; W. Loth, Daan; Soler Artigas, María; R. Joubert, Bonnie; Hodge, Emily; A. Gharib, Sina; V. Smith, Albert; Ruczinski, Ingo; Guðnason, Vilmundur; A. Mathias, Rasika; B. Harris, Tamara; N. Hansel, Nadia; J. Launer, Lenore; C. Barnes, Kathleen; Hansen, Joyanna; Albrecht, Eva; C. Aldrich, Melinda; Allerhand, Michael; Graham Barr, R.; Brusselle, Guy; Couper, David; Curjuric, Ivan; Davies, Gail; J. Deary, Ian; Dupuis, Josée; Fall, Tove; Foy, Millennia; Franceschini, Nora; Gao, Wei; Gläser, Sven; Gu, Xiangjun; B. Hancock, Dana; Heinrich, Joachim; Hofman, Albert; Imboden, Medea; Ingelsson, Erik; James, Alan; Karrasch, Stefan; Koch, Beate; B. Kritchevsky, Stephen; Kumar, Ashish; Lahousse, Lies; Guo, Li; Lind, Lars; M. Lindgren, Cecilia; Liu, Ching‐Ti; Lohman, Kurt; Lumley, Thomas; L. McArdle, Wendy; Meibohm, Bernd; P. Morris, Andrew; C. Morrison, Alanna; Musk, Bill; E. North, Kari; J. Palmer, Lyle; Probst‐Hensch, Nicole; M. Psaty, Bruce; Rivadeneira, Fernando; I. Rotter, Jerome; Schulz, Holger; J. Smith, Lewis; Sood, Akshay; M. Starr, John; P. Strachan, David; Teumer, Alexander; G. Uitterlinden, André; Völzke, Henry; Voorman, Arend; V. Wain, Louise; T. Wells, Martin; B. Wilk, Jemma; Dale Williams, O.; R. Heckbert, Susan; H. Stricker, Bruno; J. London, Stephanie; Fornage, Myriam; D. Tobin, Martin; O'connor, George; P. Hall, Ian; A. Cassano, Patricia

doi:10.1371/journal.pone.0100776

Public

Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function

Published in PLoS ONE • Jul 1, 2014

Authors:

Wenbo Tang

Matthew Kowgier

Daan W. Loth

Abstract

BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function. METHODS: We performed GWAS of the rate of change in forced expiratory volume in the first second...

Subject

Genome-wide association study

Locus (genetics)

Genetic association

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