Identification and Characterization of Pkhd1, the Mouse Orthologue of the Human ARPKD Gene

Nagasawa, Yasuyuki; Matthiesen, Sonja; F. Onuchic, Luiz; Hou, Xiaoying; Bergmann, Carsten; Esquivel, Ernie; Senderek, Jan; Ren, Zhiyong; Zeltner, Raoul; Furu, Laszlo; D. Avner, Ellis; Moser, Markus; Somlo, Stefan; M. Guay‐Woodford, Lisa; Büttner, Reinhard; Zerres, Klaus; G. Germino, Gregory

doi:10.1097/01.asn.0000030392.19694.9d

Public

Identification and Characterization of Pkhd1, the Mouse Orthologue of the Human ARPKD Gene

Published in Journal of the American Society of Nephrology • Sep 1, 2002

Authors:

Yasuyuki Nagasawa

Sonja Matthiesen

Luiz F. Onuchic

Abstract

PKHD1, the gene mutated in human autosomal recessive polycystic kidney disease has recently been identified. Its translation products are predicted to belong to a superfamily of proteins involved in the regulation of cellular adhesion and repulsion. One notable aspect of the gene is its unusually co...

Subject

Biology

Exon

Alternative splicing

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