Killing of Aspergillus fumigatus by Alveolar Macrophages Is Mediated by Reactive Oxidant Intermediates

Philippe, B.; Ibrahim-Granet, Oumaïma; Prévost, Marie‐Christine; A Gougerot-Pocidalo, M; Sánchez Pérez, María; Van der Meeren, Anne; Latgé, Jean‐Paul

doi:10.1128/iai.71.6.3034-3042.2003

Public

Killing of Aspergillus fumigatus by Alveolar Macrophages Is Mediated by Reactive Oxidant Intermediates

Published in Infection and Immunity • May 21, 2003

Authors:

B. Philippe

Oumaïma Ibrahim-Granet

Marie‐Christine Prévost

Abstract

Phagocytosis and mechanisms of killing of Aspergillus fumigatus conidia by murine alveolar macrophages (AM), which are the main phagocytic cells of the innate immunity of the lung, were investigated. Engulfment of conidia by murine AM lasts 2 h. Killing of A. fumigatus conidia by AM begins after 6 h...

Subject

Aspergillus fumigatus

Microbiology

Phagocytosis

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