Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol

S. Johnson, David; Gemelos, G.; Banér, Johan; Ryan, Allison; Cinnioğlu, Cengiz; Banjevic, Milena; M. Ross, Robert; Alper, Murat; Barrett, Brent; Frederick, Jane; Potter, D.; Behr, Barry; Rabinowitz, Matthew

doi:10.1093/humrep/dep452

Public

Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol

Published in Human Reproduction • Jan 24, 2010

Authors:

David S. Johnson

G. Gemelos

Johan Banér

Abstract

BACKGROUND: Preimplantation genetic screening (PGS) has been used in an attempt to determine embryonic aneuploidy. Techniques that use new molecular methods to determine the karyotype of an embryo are expanding the scope of PGS. METHODS: We introduce a new method for PGS, termed 'parental support', ...

Subject

Karyotype

Protocol (science)

Computational biology

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