Mesenchymal stem cells as vehicles for targeted delivery of anti‐angiogenic protein to solid tumors

Ghaedi, Mahboobe; Soleimani, Masoud; Mohammad Taghvaie, Narges; Sheikhfatollahi, Mahmood; Azadmanesh, Kayhan; S. Lotfi, Abbas; Wu, Jian

doi:10.1002/jgm.1552

Public

Mesenchymal stem cells as vehicles for targeted delivery of anti‐angiogenic protein to solid tumors

Published in The Journal of Gene Medicine • Mar 1, 2011

Authors:

Mahboobe Ghaedi

Masoud Soleimani

Narges Mohammad Taghvaie

Abstract

BACKGROUND: Inhibition of tumor-induced angiogenesis may restrict tumor growth and metastasis. Long-term systemic delivery of angiogenic inhibitors is associated with toxicity, as well as other severe side-effects. The utility of cells as vehicles for gene therapy to deliver therapeutic molecules ha...

Subject

Mesenchymal stem cell

Cytotoxicity

Angiogenesis

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!