In vitro activity of micafungin (FK-463) against Candida spp.: microdilution, time-kill, and postantifungal-effect studies.

EJ, Ernst; EE, Roling; CR, Petzold; DJ, Keele; ME, Klepser

doi:10.1128/aac.46.12.3846-3853.2002

Public

In vitro activity of micafungin (FK-463) against Candida spp.: microdilution, time-kill, and postantifungal-effect studies.

Shared by NobleBlocks on Dec 1, 2002 • 12:00 AM UTC

Authors:

Ernst EJ

Roling EE

Petzold CR

Abstract

We evaluated the in vitro activity of the new echinocandin antifungal micafungin against Candida spp. using microdilution and time-kill methods. Additionally, we examined the postantifungal effect (PAFE) of micafungin. Finally, we evaluated the effect of the addition of serum and plasma on the MIC o...

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