Global mapping of c-Myc binding sites and target gene networks in human B cells

Zeller, Karen; Zhao, Xiaodong; W. H. Lee, Charlie; Ping Chiu, Kuo; Yao, Fei; T. Yustein, Jason; Ooi, Hong; L. Orlov, Yuriy; Shahab, Atif; Choong Yong, How; Fu, Yutao; Weng, Zhiping; A. Kuznetsov, Vladimir; Sung, Wing‐Kin; Ruan, Yijun; V. Dang, Chi; Wei, Chia‐Lin

doi:10.1073/pnas.0604129103

Public

Global mapping of c-Myc binding sites and target gene networks in human B cells

Published in Proceedings of the National Academy of Sciences • Nov 8, 2006

Authors:

Karen Zeller

Xiaodong Zhao

Charlie W. H. Lee

Abstract

The protooncogene MYC encodes the c-Myc transcription factor that regulates cell growth, cell proliferation, cell cycle, and apoptosis. Although deregulation of MYC contributes to tumorigenesis, it is still unclear what direct Myc-induced transcriptomes promote cell transformation. Here we provide a...

Subject

Biology

Carcinogenesis

Transcription factor

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!