<i>PGC-1</i>
                    α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

Zheng, Bin; Liao, Zhixiang; J. Locascio, Joseph; A. Lesniak, Kristen; S. Roderick, Sarah; L. Watt, Marla; C. Eklund, Aron; Zhang-James, Yanli; D. Kim, Peter; A. Hauser, Michael; Grünblatt, Edna; B. Moran, Linda; A. Mandel, Silvia; Riederer, Peter; M. Miller, Renee; J. Federoff, Howard; Wüllner, Ullrich; Papapetropoulos, Spyridon; B. Youdim, Moussa; Cantuti-Castelvetri, Ippolita; B. Young, Anne; M. Vance, Jeffery; L. Davis, Richard; C. Hedreen, John; H. Adler, Charles; G. Beach, Thomas; B. Graeber, Manuel; A. Middleton, Frank; Rochet, Jean-Christophe; R. Scherzer, Clemens; Global PD Gene Expression (GPEX) Consortium, the

doi:10.1126/scitranslmed.3001059

Public

PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

Shared by NobleBlocks on Oct 6, 2010 • 12:00 AM UTC

Authors:

Bin Zheng

Zhixiang Liao

Joseph J. Locascio

Abstract

Abnormal expression of genes for energy regulation in Parkinson’s disease patients identifies a master regulator as a possible therapeutic target for early intervention.

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