MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

A. Boon, Reinier; Seeger, Timon; Heydt, Susanne; Fischer, Ariane; Hergenreider, Eduard; J.G. Horrevoets, Anton; Vinciguerra, Manlio; Rosenthal, Nadia; Sciacca, Sergio; Pilato, Michele; van Heijningen, Paula; Essers, Jeroen; P. Brandes, Ralf; M. Zeiher, Andreas; Dimmeler, Stefanie

doi:10.1161/circresaha.111.255737

Public

MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation

Published in Circulation Research • Sep 9, 2011

Authors:

Reinier A. Boon

Timon Seeger

Susanne Heydt

Abstract

RATIONALE: Aging represents a major risk factor for coronary artery disease and aortic aneurysm formation. MicroRNAs (miRs) have emerged as key regulators of biological processes, but their role in age-associated vascular pathologies is unknown. OBJECTIVE: We aim to identify miRs in the vasculature ...

Subject

Downregulation and upregulation

Extracellular matrix

Aorta

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