Interferon-α2a and 13-cis-retinoic acid with radiationtreatment for high-grade glioma

O. Dillman, Robert; M. Shea, William; F. Tai, D.; Mahdavi, Khosrow; M. Barth, Neil; R. Kharkar, Bharati; M. Poor, Marshall; K. Church, Curtis; DePriest, Carol

doi:10.1093/neuonc/3.1.35

Public

Interferon-α2a and 13-cis-retinoic acid with radiationtreatment for high-grade glioma

Published in Neuro-Oncology • Jan 1, 2001

Authors:

Robert O. Dillman

William M. Shea

D. F. Tai

Abstract

Interferon-alpha (IFN-alpha) has been safely given concurrently with radiation therapy (RT) in treating gliomas. As single agents, both IFN-alpha and cis-retinoic acid (CRA) have produced objective tumor regressions in patients with recurrent gliomas. In vitro, IFN-alpha2a and CRA enhance radiation ...

Subject

Retinoic acid

Glioma

Interferon

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