Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

Hacke, Werner; Kaste, Markku; Bluhmki, Erich; Brozman, M; Dávalos, Antoni; Guidetti, Donata; Larrue, Vincent; R. Lees, Kennedy; Medeghri, Zakaria; Machnig, Thomas; Schneider, Dietmar; von Kummer, Rüdiger; Wahlgren, Nils; Toni, Danilo

doi:10.1056/nejmoa0804656

Public

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

Published in New England Journal of Medicine • Sep 24, 2008

Authors:

Werner Hacke

Markku Kaste

Erich Bluhmki

Abstract

BACKGROUND: Intravenous thrombolysis with alteplase is the only approved treatment for acute ischemic stroke, but its efficacy and safety when administered more than 3 hours after the onset of symptoms have not been established. We tested the efficacy and safety of alteplase administered between 3 a...

Subject

Medicine

Thrombolysis

Stroke (engine)

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