Regulation of the Actin Cytoskeleton by Thrombin in Human Endothelial Cells: Role of Rho Proteins in Endothelial Barrier Function

Vouret‐Craviari, Valérie; Boquet, Patrice; Pouysségur, Jacques; Van Obberghen‐Schilling, Ellen

doi:10.1091/mbc.9.9.2639

Public

Regulation of the Actin Cytoskeleton by Thrombin in Human Endothelial Cells: Role of Rho Proteins in Endothelial Barrier Function

Published in Molecular Biology of the Cell • Sep 1, 1998

Authors:

Valérie Vouret‐Craviari

Patrice Boquet

Jacques Pouysségur

Abstract

Endothelial barrier function is regulated at the cellular level by cytoskeletal-dependent anchoring and retracting forces. In the present study we have examined the signal transduction pathways underlying agonist-stimulated reorganization of the actin cytoskeleton in human umbilical vein endothelial...

Subject

Cell biology

Biology

Stress fiber

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