Critical Role of Vascular Endothelial Growth Factor Secreted by Mesenchymal Stem Cells in Hyperoxic Lung Injury

Sil Chang, Yun; Yoon Ahn, So; Bae Jeon, Hong; Kyung Sung, Dong; Sun Kim, Eun; In Sung, Se; Soo Yoo, Hye; Jin Choi, Soo; Il Oh, Won; Soon Park, Won

doi:10.1165/rcmb.2013-0385oc

Public

Critical Role of Vascular Endothelial Growth Factor Secreted by Mesenchymal Stem Cells in Hyperoxic Lung Injury

Published in American Journal of Respiratory Cell and Molecular Biology • Mar 26, 2014

Authors:

Yun Sil Chang

So Yoon Ahn

Hong Bae Jeon

Abstract

Intratracheal transplantation of human umbilical cord blood (UCB)-derived mesenchymal stem cells (MSCs) protects against neonatal hyperoxic lung injury by a paracrine rather than a regenerative mechanism. However, the role of paracrine factors produced by the MSCs, such as vascular endothelial growt...

Subject

Mesenchymal stem cell

Cell biology

Lung

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!