Genetic Determinants of Response to Clopidogrel and Cardiovascular Events

Simon, Tabassome; Verstuyft, Céline; Mary‐Krause, Murielle; Quteineh, Lina; Drouet, Élodie; Méneveau, Nicolas; Gabríel Steg, Philippe; Ferrières, Jean; Danchin, Nicolas; Becquemont, Laurent

doi:10.1056/nejmoa0808227

Public

Genetic Determinants of Response to Clopidogrel and Cardiovascular Events

Published in New England Journal of Medicine • Dec 22, 2008

Authors:

Tabassome Simon

Céline Verstuyft

Murielle Mary‐Krause

Abstract

BACKGROUND: Pharmacogenetic determinants of the response of patients to clopidogrel contribute to variability in the biologic antiplatelet activity of the drug. The effect of these determinants on clinical outcomes after an acute myocardial infarction is unknown. METHODS: We consecutively enrolled 2...

Subject

Medicine

Clopidogrel

Internal medicine

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