Emergence of penicillin-nonsusceptible Streptococcus pneumoniae clones expressing serotypes not present in the antipneumococcal conjugate vaccine.

N, Porat; A, Arguedas; BG, Spratt; R, Trefler; E, Brilla; C, Loaiza; D, Godoy; N, Bilek; R, Dagan

doi:10.1086/425908

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Emergence of penicillin-nonsusceptible Streptococcus pneumoniae clones expressing serotypes not present in the antipneumococcal conjugate vaccine.

Shared by NobleBlocks on Nov 11, 2004 • 12:00 AM UTC

Authors:

Porat N

Arguedas A

Spratt BG

Abstract

Background Penicillin-nonsusceptible Streptococcus pneumoniae isolates are confined mainly to a few serogroups. Capsular transformation may serve as a mechanism for spreading antibiotic resistance to new serotypes.Methods Antibiogram and molecular typing, by pulsed-field gel electrophoresis (PFGE), ...

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