Increased Risk of Arrhythmic Events in Long-QT Syndrome With Mutations in the Pore Region of the Human Ether-a-go-go–Related Gene Potassium Channel

J. Moss, Arthur; Zaręba, Wojciech; S. Kaufman, Elizabeth; Gartman, Eric; R. Peterson, Derick; Benhorin, Jesaia; A. Towbin, Jeffrey; T. Keating, Mark; G. Priori, Silvia; J. Schwartz, Peter; Michael Vincent, G.; L. Robinson, Jennifer; Andrews, Mark; Feng, Changyong; J. Hall, William; Medina, Aharon; Zhang, Li; Wang, Zhiqing

doi:10.1161/hc0702.105124

Public

Increased Risk of Arrhythmic Events in Long-QT Syndrome With Mutations in the Pore Region of the Human Ether-a-go-go–Related Gene Potassium Channel

Published in Circulation • Feb 19, 2002

Authors:

Arthur J. Moss

Wojciech Zaręba

Elizabeth S. Kaufman

Abstract

BACKGROUND: The hereditary long-QT syndrome is characterized by prolonged ventricular repolarization and a variable clinical course with arrhythmia-related syncope and sudden death. Mutations involving the human ether-a-go-go-related gene (HERG) channel are responsible for the LQT2 form of long-QT s...

Subject

hERG

QT interval

Long QT syndrome

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