Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol.

N. Jamal, Zoeb; Martin, A; Gómez‐Muñoz, Antonio; N. Brindley, David

doi:10.1016/s0021-9258(18)49945-0

Public

Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol.

Published in Journal of Biological Chemistry • Feb 1, 1991

Authors:

Zoeb N. Jamal

A Martin

Antonio Gómez‐Muñoz

Abstract

Assays for two distinct phosphatidate phosphohydrolase activities were established based upon a differential inhibition by N-ethylmaleimide (NEM). The activity that is insensitive to this reagent in rat liver is predominantly in the plasma membrane fraction, whereas the NEM-sensitive activity is in ...

Subject

Endoplasmic reticulum

Cytosol

Membrane

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