Ruminococcin A, a New Lantibiotic Produced by a <i>Ruminococcus gnavu</i> s Strain Isolated from Human Feces

Dabard, J.; Bridonneau, Chantal; Phillipe, C.; Anglade, Patricia; Mollé, Daniel; Nardi, M.; Ladiré, M.; Girardin, H; Marcille, F.; Gómez, Ana; Fons, Michel

doi:10.1128/aem.67.9.4111-4118.2001

Public

Ruminococcin A, a New Lantibiotic Produced by a Ruminococcus gnavu s Strain Isolated from Human Feces

Published in Applied and Environmental Microbiology • Sep 1, 2001

Authors:

J. Dabard

Chantal Bridonneau

C. Phillipe

Abstract

When cultivated in the presence of trypsin, the Ruminococcus gnavus E1 strain, isolated from a human fecal sample, was able to produce an antibacterial substance that accumulated in the supernatant. This substance, called ruminococcin A, was purified to homogeneity by reverse-phase chromatography. I...

Subject

Lantibiotics

Bacteriocin

Edman degradation

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