Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis

M. Ginzler, Ellen; Anne Dooley, Mary; Aranow, Cynthia; Kim, Mimi; P. Buyon, Jill; T. Merrill, Joan; Petri, Michelle; S. Gilkeson, Gary; J. Wallace, Daniel; H. Weisman, Michael; B. Appel, Gerald

doi:10.1056/nejmoa043731

Public

Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis

Published in New England Journal of Medicine • Nov 23, 2005

Authors:

Ellen M. Ginzler

Mary Anne Dooley

Cynthia Aranow

Abstract

BACKGROUND: Since anecdotal series and small, prospective, controlled trials suggest that mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are desirable. METHODS: We conducted a 24-week randomized, open-label, noninferiority trial comparing oral mycophenolate mofeti...

Subject

Medicine

Cyclophosphamide

Lupus nephritis

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