A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

J. van de Vijver, Marc; D. He, Yudong; van ‘t Veer, Laura; Dai, Hongyue; A. M. Hart, Augustinus; W. Voskuil, Dorien; J. Schreiber, George; L. Peterse, Johannes; Roberts, Chris; J. Marton, Matthew; L Parrish, Mark; E. Atsma, Douwe; Witteveen, Anke; M. Glas, Annuska; Delahaye, Leonie; van der Velde, Tony; Bartelink, Harry; Rodenhuis, Sjoerd; T. Rutgers, Emiel; Friend, Stephen; Bernards, René

doi:10.1056/nejmoa021967

Public

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

Published in New England Journal of Medicine • Dec 18, 2002

Authors:

Marc J. van de Vijver

Yudong D. He

Laura van ‘t Veer

Abstract

BACKGROUND: A more accurate means of prognostication in breast cancer will improve the selection of patients for adjuvant systemic therapy. METHODS: Using microarray analysis to evaluate our previously established 70-gene prognosis profile, we classified a series of 295 consecutive patients with pri...

Subject

Medicine

Hazard ratio

Breast cancer

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