Rapid, Low-Technology MIC Determination with Clinical <i>Mycobacterium tuberculosis</i> Isolates by Using the Microplate Alamar Blue Assay

G. Franzblau, Scott; Witzig, Richard; C. McLaughlin, James; Torres, Patricia; Madico, Guillermo; M. Hernández, Antonio; T. Degnan, Michelle; B. Cook, Mary; K. Quenzer, Virginia; M. Ferguson, Robert; H. Gilman, Robert

doi:10.1128/jcm.36.2.362-366.1998

Public

Rapid, Low-Technology MIC Determination with Clinical Mycobacterium tuberculosis Isolates by Using the Microplate Alamar Blue Assay

Published in Journal of Clinical Microbiology • Feb 1, 1998

Authors:

Scott G. Franzblau

Richard Witzig

James C. McLaughlin

Abstract

A colorimetric, microplate-based Alamar Blue assay (MABA) method was used to determine the MICs of isoniazid (INH), rifampin, streptomycin (SM), and ethambutol (EMB) for 34 Peruvian Mycobacterium tuberculosis isolates (including both pansensitive and multidrug-resistant strains) and the H37Rv strain...

Subject

Isoniazid

Ethambutol

Mycobacterium tuberculosis

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