Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

T. Hennessy, Bryan; Gonzalez-Angulo, Ana-Maria; Stemke‐Hale, Katherine; Z. Gilcrease, Michael; Krishnamurthy, Savitri; Lee, Ju‐Seog; Fridlyand, Jane; A. Şahin, Ayşegül; Agarwal, Roshan; Joy, Corwin; Liu, Wenbin; Stivers, David; Baggerly, Keith; Carey, Mark; Lluch, Aňa; Monteagudo, Carlos; He, Xiaping; Weigman, Victor; Fan, Cheng; Palazzo, Juan; N. Hortobágyi, Gabriel; K. Nolden, Laura; J. Wang, Nicholas; Valero, Vicente; W. Gray, Joe; M. Perou, Charles; B. Mills, Gordon

doi:10.1158/0008-5472.can-08-3441

Public

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

Published in Cancer Research • May 12, 2009

Authors:

Bryan T. Hennessy

Ana-Maria Gonzalez-Angulo

Katherine Stemke‐Hale

Abstract

Metaplastic breast cancers (MBC) are aggressive, chemoresistant tumors characterized by lineage plasticity. To advance understanding of their pathogenesis and relatedness to other breast cancer subtypes, 28 MBCs were compared with common breast cancers using comparative genomic hybridization, transc...

Subject

Biology

Breast cancer

Cancer research

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