RNA-seq of 272 gliomas revealed a novel, recurrent <i>PTPRZ1-MET</i> fusion transcript in secondary glioblastomas

Bao, Zhaoshi; Chen, Hui-Min; Yang, Ming-Yu; Zhang, Chuan-Bao; Yu, Kai; Ye, Wan-Lu; Hu, Bo-Qiang; Yan, Wei; Zhang, Wei; Akers, Johnny; Ramakrishnan, Valya; Li, Jie; S. Carter, Bob; Liu, Yan-Wei; Hu, Hui-Min; Wang, Zheng; Li, Mingyang; Yao, Kun; Qiu, Xiao-Guang; Kang, Chunsheng; You, Yong-ping; Fan, Xiao-Long; Song, Wei; Li, Rui-qiang; Su, Xiao‐Dong; C. Chen, Clark; Jiang, Tao

doi:10.1101/gr.165126.113

Public

RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas

Published in Genome Research • Aug 18, 2014

Authors:

Zhaoshi Bao

Hui-Min Chen

Ming-Yu Yang

Abstract

Studies of gene rearrangements and the consequent oncogenic fusion proteins have laid the foundation for targeted cancer therapy. To identify oncogenic fusions associated with glioma progression, we catalogued fusion transcripts by RNA-seq of 272 gliomas. Fusion transcripts were more frequently foun...

Subject

Fusion gene

Fusion transcript

Biology

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