Subthalamic Nucleus Stimulation in Severe Obsessive–Compulsive Disorder

Mallet, Luc; Polosan, Mircea; Jaafari, Nématollah; Baup, Nicolas; Welter, Marie‐Laure; Fontaine, Denys; Tézenas du Montcel, Sophie; Yelnik, Jérôme; Chéreau, Isabelle; Arbus, Christophe; Raoul, Sylvie; Aouizerate, Bruno; Damier, Philippe; Chabardès, Stéphan; Czernecki, Virginie; Ardouin, Claire; Krebs, Marie‐Odile; Bardinet, Éric; Chaynes, Patrick; Burbaud, Pierre; Cornu, Philippe; Derost, Philippe; Bougerol, Thierry; Bataille, B.; Mattei, Vianney; Dormont, Didier; Devaux, Bertrand; Vérin, Marc; Houéto, Jean‐Luc; Pollak, Pierre; Benabid, Alim‐Louis; Agid, Yves; Krack, Paul; Millet, Bruno; Pélissolo, Antoine

doi:10.1056/nejmoa0708514

Public

Subthalamic Nucleus Stimulation in Severe Obsessive–Compulsive Disorder

Published in New England Journal of Medicine • Nov 12, 2008

Authors:

Luc Mallet

Mircea Polosan

Nématollah Jaafari

Abstract

BACKGROUND: Severe, refractory obsessive-compulsive disorder (OCD) is a disabling condition. Stimulation of the subthalamic nucleus, a procedure that is already validated for the treatment of movement disorders, has been proposed as a therapeutic option. METHODS: In this 10-month, crossover, double-...

Subject

Subthalamic nucleus

Stimulation

Deep brain stimulation

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