Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis

P. Hayhurst, Graham; Lee, Ying‐Hue; Lambert, Gilles; M. Ward, Jerrold; J. Gonzalez, Frank

doi:10.1128/mcb.21.4.1393-1403.2001

Public

Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis

Published in Molecular and Cellular Biology • Feb 1, 2001

Authors:

Graham P. Hayhurst

Ying‐Hue Lee

Gilles Lambert

Abstract

The numerous functions of the liver are controlled primarily at the transcriptional level by the concerted actions of a limited number of hepatocyte-enriched transcription factors (hepatocyte nuclear factor 1alpha [HNF1alpha], -1beta, -3alpha, -3beta, -3gamma, -4alpha, and -6 and members of the c/eb...

Subject

Hepatocyte nuclear factor 4

Hepatocyte nuclear factors

Biology

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