FOXL2 activates <i>P450 aromatase</i> gene transcription: towards a better characterization of the early steps of mammalian ovarian development

Pannetier, Maëlle; Fabre, Stéphane; Batista, Frank; Kocer, Ayhan; Renault, Lauriane; Jolivet, Geneviève; Mandon‐Pepin, Béatrice; Cotinot, Corinne; A. Veitia, Reiner; Pailhoux, Éric

doi:10.1677/jme.1.01947

Public

FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development

Published in Journal of Molecular Endocrinology • Feb 21, 2006

Authors:

Maëlle Pannetier

Stéphane Fabre

Frank Batista

Abstract

Previous studies have equated FOXL2 as a crucial actor in the ovarian differentiation process in different vertebrate species. Its transcriptional extinction in the polled intersex syndrome (PIS) leads primarily to a drastic decrease of aromatase (CYP19) expression in the first steps of goat ovarian...

Subject

Aromatase

Biology

Somatic cell

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