Matrilysin-specific antisense oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude mouse model

Hasegawa, Satoshi; Koshikawa, Naohiko; Momiyama, Nobuyoshi; Moriyama, Kayano; Ichikawa, Yasushi; Ishikawa, Takashi; Mitsuhashi, Masato; Shimada, Hiroshi; Miyazaki, Kaoru

doi:10.1002/(sici)1097-0215(19980610)76:6<812::aid-ijc8>3.0.co;2-0

Public

Matrilysin-specific antisense oligonucleotide inhibits liver metastasis of human colon cancer cells in a nude mouse model

Published in International Journal of Cancer • Jun 10, 1998

Authors:

Satoshi Hasegawa

Naohiko Koshikawa

Nobuyoshi Momiyama

Abstract

Human colon cancer frequently develops liver metastasis. Matrilysin (MMP-7), the smallest member of the matrix metalloproteinase (MMP) family, is commonly produced by human colon carcinoma cells and has been suggested to be involved in the progression and metastasis of this type of cancer. In the pr...

Subject

Matrilysin

Metastasis

Cancer research

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