Magnetically Responsive Smart Nanoparticles for Cancer Treatment with a Combination of Magnetic Hyperthermia and Remote-Control Drug Release

Hayashi, Koichiro; Nakamura, Michihiro; Miki, Hirokazu; Ozaki, Shuji; Abe, Masahiro; Matsumoto, Toshio; Sakamoto, Wataru; Yogo, Toshinobu; Ishimura, Kazunori

doi:10.7150/thno.9199

Public

Magnetically Responsive Smart Nanoparticles for Cancer Treatment with a Combination of Magnetic Hyperthermia and Remote-Control Drug Release

Published in Theranostics • Jan 1, 2014

Authors:

Koichiro Hayashi

Michihiro Nakamura

Hirokazu Miki

Abstract

We report the synthesis of smart nanoparticles (NPs) that generate heat in response to an alternating current magnetic field (ACMF) and that sequentially release an anticancer drug (doxorubicin, DOX). We further study the in vivo therapeutic efficacy of the combination of magnetic hyperthermia (MHT)...

Subject

Doxorubicin

Hyperthermia

Magnetic hyperthermia

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