Clinical Significance and Therapeutic Potential of the Programmed Death-1 Ligand/Programmed Death-1 Pathway in Human Pancreatic Cancer

Nomi, Takeo; Sho, Masayuki; Akahori, Takahiro; Hamada, Kaoru; Kubo, Atsushi; Kanehiro, Hiromichi; Nakamura, Shinji; Enomoto, Koji; Yagita∥, Hideo; Azuma, Miyuki; Nakajima, Yoshiyuki

doi:10.1158/1078-0432.ccr-06-2746

Public

Clinical Significance and Therapeutic Potential of the Programmed Death-1 Ligand/Programmed Death-1 Pathway in Human Pancreatic Cancer

Published in Clinical Cancer Research • Apr 1, 2007

Authors:

Takeo Nomi

Masayuki Sho

Takahiro Akahori

Abstract

PURPOSE: The programmed death-1 ligand/programmed death-1 (PD-L/PD-1) pathway has been recently suggested to play a pivotal role in the immune evasion of tumors from host immune system. In this study, we tried to reveal the clinical importance and therapeutic potential of the PD-L/PD-1 pathway in pa...

Subject

Pancreatic cancer

PD-L1

Medicine

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