Specific Glycosylation of Membrane Proteins in Epithelial Ovarian Cancer Cell Lines: Glycan Structures Reflect Gene Expression and DNA Methylation Status

Anugraham, Merrina; Jacob, Francis; Nixdorf, Sheri; Everest‐Dass, Arun; Heinzelmann‐Schwarz, Viola; H. Packer, Nicolle

doi:10.1074/mcp.m113.037085

Public

Specific Glycosylation of Membrane Proteins in Epithelial Ovarian Cancer Cell Lines: Glycan Structures Reflect Gene Expression and DNA Methylation Status

Published in Molecular & Cellular Proteomics • May 23, 2014

Authors:

Merrina Anugraham

Francis Jacob

Sheri Nixdorf

Abstract

Epithelial ovarian cancer is the fifth most common cause of cancer in women worldwide bearing the highest mortality rate among all gynecological cancers. Cell membrane glycans mediate various cellular processes such as cell signaling and become altered during carcinogenesis. The extent to which glyc...

Subject

Glycosylation

Glycan

DNA methylation

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