Increased sialylation of oligosaccharides on IgG paraproteins--a potential new tumour marker in multiple myeloma.

Fleming, Simon; V. Smith, Sandra; P. Knowles, Donald; W. Skillen, A.; H. Self, Colin

doi:10.1136/jcp.51.11.825

Public

Increased sialylation of oligosaccharides on IgG paraproteins--a potential new tumour marker in multiple myeloma.

Published in Journal of Clinical Pathology • Nov 1, 1998

Authors:

Simon Fleming

Sandra V. Smith

Donald P. Knowles

Abstract

AIMS: To investigate whether changes in carbohydrate structure of IgG are related to malignancy and stage of disease in myeloma and monoclonal gammopathy of uncertain significance (MGUS). METHODS: 61 patients were studied at diagnosis: 14 with MGUS, nine with stage I multiple myeloma, 11 with stage ...

Subject

Multiple myeloma

Chemistry

Myeloma protein

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