Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay

Thomas, Philip; Umegaki, Keizo; Fenech, Michael

doi:10.1093/mutage/18.2.187

Public

Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay

Published in Mutagenesis • Mar 1, 2003

Authors:

Philip Thomas

Keizo Umegaki

Michael Fenech

Abstract

We have performed experiments using the WIL2-NS human B lymphoblastoid cell line and primary human lymphocytes to: (i). determine the importance of including measurements of nucleoplasmic bridges (NPB) in the cytokinesis-block micronucleus (CBMN) assay; (ii). provide evidence that NPB originate from...

Subject

Dicentric chromosome

Ring chromosome

Micronucleus test

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!