Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

Pérez-Gómez, Eduardo; Andradas, Clara; Blasco-Benito, Sandra; M. Caffarel, María; García-Taboada, Elena; Villa‐Morales, María; Moreno, Estefanía; Hamann, Sigrid; Martín-Villar, Ester; M Flores, Juana; Wenners, Antonia; Alkatout, İbrahim; Klapper, Wolfram; Röcken, Christoph; Bronsert, Peter; Stickeler, Elmar; Staebler, Annette; Bauer, M.; Arnold, Norbert; Soriano, Joaquím; Pérez‐Martínez, Manuel; Megı́as, Diego; Moreno‐Bueno, Gema; Ortega‐Gutiérrez, Silvia; Artola, Marta; Vázquez‐Villa, Henar; Quintanilla, Miguel; Fernández‐Piqueras, José; I. Canela, Enric; J. McCormick, Peter; Guzmán, Manuel; Sánchez, Cristina

doi:10.1093/jnci/djv077

Public

Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

Published in JNCI Journal of the National Cancer Institute • Apr 8, 2015

Authors:

Eduardo Pérez-Gómez

Clara Andradas

Sandra Blasco-Benito

Abstract

BACKGROUND: Pharmacological activation of cannabinoid receptors elicits antitumoral responses in different cancer models. However, the biological role of these receptors in tumor physio-pathology is still unknown. METHODS: We analyzed CB2 cannabinoid receptor protein expression in two series of 166 ...

Subject

Cannabinoid receptor

Breast cancer

Cannabinoid receptor type 2

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