Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

Significance Reactive sulfur-containing compounds, such as l -cysteine hydropersulfide (CysSSH), reportedly form in mammals. However, the biological relevance of these reactive sulfur species remains unclear. We determined that CysSSH was synthesized from cystine by cystathionine β-synthase and cyst... View More