Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

Gao, Qiang; Wang, Xiaoying; Qiu, Shuang‐Jian; Yamato, Ichiro; Sho, Masayuki; Nakajima, Yoshiyuki; Zhou, Jian; Li, Baizhou; Shi, Yongyong; Xiao, Yongsheng; Xu, Yang; Fan, Jia

doi:10.1158/1078-0432.ccr-08-1608

Public

Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

Published in Clinical Cancer Research • Feb 1, 2009

Authors:

Qiang Gao

Xiaoying Wang

Shuang‐Jian Qiu

Abstract

PURPOSE: The aberrant expression of programmed cell death 1 ligands 1 and 2 (PD-Ls) on tumor cells dampens antitumor immunity, resulting in tumor immune evasion. In this study, we investigated the expression of PD-Ls in human hepatocellular carcinoma (HCC) to define their prognostic significance aft...

Subject

Granzyme B

Hepatocellular carcinoma

Tissue microarray

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