Results of a Randomized Study of Preradiation Chemotherapy Versus Radiotherapy Alone for Nonmetastatic Medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children’s Cancer Study Group PNET-3 Study

Taylor, Roger; C. Bailey, Clifford; Robinson, Kath; Weston, Claire; W. Ellison, David; W. Ironside, James; Lucraft, Helen; J. Gilbertson, Richard; Tait, Diana; Walker, David; Pizer, Barry; Imeson, John; S. Lashford, L.

doi:10.1200/jco.2003.05.116

Public

Results of a Randomized Study of Preradiation Chemotherapy Versus Radiotherapy Alone for Nonmetastatic Medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children’s Cancer Study Group PNET-3 Study

Published in Journal of Clinical Oncology • Apr 15, 2003

Authors:

Roger Taylor

Clifford C. Bailey

Kath Robinson

Abstract

PURPOSE: To determine whether preradiotherapy (RT) chemotherapy would improve outcome for Chang stage M0-1 medulloblastoma when compared with RT alone. Chemotherapy comprised vincristine 1.5 mg/m2 weekly for 10 weeks and four cycles of etoposide 100 mg/m2 daily for 3 days, and carboplatin 500 mg/m2 ...

Subject

Medicine

Chemotherapy

Medulloblastoma

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