An EORTC International Multicenter Randomized Trial (EORTC Number 19923) Comparing Two Dosages of Liposomal Amphotericin B for Treatment of Invasive Aspergillosis

Ellis, Michael; J. Spence, David; de Pauw, Ben; Meunier, F.; Marinus, A.; Collette, Laurence; Sylvester, Richard; F. Meis, Jacques; Boogaerts, M.; Selleslag, Dominik; Krčméry, V.; von Sinner, W.; C. MacDonald, Paul; Doyen, Chantal; Vandercam, Bernard

doi:10.1086/515033

Public

An EORTC International Multicenter Randomized Trial (EORTC Number 19923) Comparing Two Dosages of Liposomal Amphotericin B for Treatment of Invasive Aspergillosis

Published in Clinical Infectious Diseases • Dec 1, 1998

Authors:

Michael Ellis

David J. Spence

Ben de Pauw

Abstract

This is the first completed prospective randomized clinical efficacy trial of antifungals in the treatment of invasive aspergillosis (IA) and the first to compare the clinical efficacy of two dosages of liposomal amphotericin B (L-AmB) for IA in neutropenic patients with cancer or those undergoing b...

Subject

Medicine

Dose

Aspergillosis

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