Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

Khademi, Mohsen; Kockum, Ingrid; Andersson, Magnus; Iacobaeus, Ellen; Brundin, Lou; Sellebjerg, Finn; Hillert, Jan; Piehl, Fredrik; Olsson, Tomas

doi:10.1177/1352458510389102

Public

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

Published in Multiple Sclerosis Journal • Dec 6, 2010

Authors:

Mohsen Khademi

Ingrid Kockum

Magnus Andersson

Abstract

BACKGROUND: Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of MS activity. Levels decrease upon effective treatments. OBJECTIVE: Here we validate the potential role of CSF CXCL13 as a bio...

Subject

CXCL13

Multiple sclerosis

Medicine

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