Serum CA19-9 Is Significantly Upregulated up to 2 Years before Diagnosis with Pancreatic Cancer: Implications for Early Disease Detection

P. O’Brien, Darragh; S. Sandanayake, Neomal; Jenkinson, Claire; Gentry‐Maharaj, Aleksandra; Apostolidou, Sophia; Fourkala, Evangelia‐Ourania; Camuzeaux, Stéphane; Blyuss, Oleg; Gunu, Richard; Dawnay, Anne; Zaikin, Alexey; C. Smith, Ross; Jacobs, Ian; Menon, Usha; Costello, Eithne; P. Pereira, Stephen; F. Timms, John

doi:10.1158/1078-0432.ccr-14-0365

Public

Serum CA19-9 Is Significantly Upregulated up to 2 Years before Diagnosis with Pancreatic Cancer: Implications for Early Disease Detection

Published in Clinical Cancer Research • Jun 18, 2014

Authors:

Darragh P. O’Brien

Neomal S. Sandanayake

Claire Jenkinson

Abstract

PURPOSE: Biomarkers for the early detection of pancreatic cancer are urgently needed. The primary objective of this study was to evaluate whether increased levels of serum CA19-9, CA125, CEACAM1, and REG3A are present before clinical presentation of pancreatic cancer and to assess the performance of...

Subject

Pancreatic cancer

Cancer

Medicine

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