Association of a functional single‐nucleotide polymorphism of PTPN22 , encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus

Orozco, Gisela; Sánchez, Elena; Á. González‐Gay, Miguel; Ángel López‐Nevot, Miguel; Torres, Belén; Cáliz, Rafael; Ortego‐Centeno, Norberto; Jiménez-Alonso, J; Pascual‐Salcedo, Dora; Balsa, Alejandro; de Pablo, Rosario; Núñez‐Roldán, Antonio; Francisca González-Escribano, Ma.; Martı́n, Javier

doi:10.1002/art.20771

Public

Association of a functional single‐nucleotide polymorphism of PTPN22 , encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus

Published in Arthritis & Rheumatism • Jan 1, 2005

Authors:

Gisela Orozco

Elena Sánchez

Miguel Á. González‐Gay

Abstract

OBJECTIVE: To assess the possible association between the PTPN22 gene 1858C-->T polymorphism and the predisposition and clinical expression of 2 systemic autoimmune diseases, rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). METHODS: Our study population consisted of 826 RA patients,...

Subject

PTPN22

Medicine

Rheumatoid arthritis

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