Gastric intestinal metaplasia as detected by a monoclonal antibody is highly associated with gastric adenocarcinoma

K. Mirza, Zafar; K Das, K; Slate, J; N Mapitigama, R; S Amenta, P; H Griffel, L; Ramsundar, L; Watari, J; Yokota, K; Tanabe, H; Sato, T; Kohgo, Y; M Das, K

doi:10.1136/gut.52.6.807

Public

Gastric intestinal metaplasia as detected by a monoclonal antibody is highly associated with gastric adenocarcinoma

Published in Gut • May 9, 2003

Authors:

Zafar K. Mirza

K K Das

J Slate

Abstract

BACKGROUND: Some forms of gastric intestinal metaplasia (GIM) may be precancerous but the cellular phenotype that predisposes to gastric carcinogenesis is not well characterised. Mucin staining, as a means of differentiating GIM, is difficult. A monoclonal antibody, mAb Das-1 (initially called 7E(12...

Subject

Monoclonal antibody

Adenocarcinoma

Intestinal metaplasia

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