Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial

Ruzicka, Thomas; Lynde, Charles; B. E. Jemec, Gregor; L. Diepgen, Thomas; Berth‐Jones, J.; Coenraads, Pieter‐Jan; Kaszuba, Andrzej; Bissonnette, Robert; Varjonen, E.; Holló, Péter; Cambazard, F.; Lahfa, M.; Elsner, Peter; Nyberg, Fredrik; Svensson, Åke; C. Brown, Thomas; Harsch, Martin; Maares, J.

doi:10.1111/j.1365-2133.2008.08487.x

Public

Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial

Published in British Journal of Dermatology • Feb 21, 2008

Authors:

Thomas Ruzicka

Charles Lynde

Gregor B. E. Jemec

Abstract

BACKGROUND: Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studies have investigated new therapies in this setting. OBJECTIVES: To assess the efficacy and safety of oral...

Subject

Medicine

Placebo

Refractory (planetary science)

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