Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

Villar, Luis; H. Dayan, Gustavo; Luis Arredondo-Garcı́a, José; Maribel Rivera, Doris; Venâncio da Cunha, Rivaldo; Deseda, Carmen; Reynales, Humberto; Selma Neves da Costa, Maria; O Morales-Ramirez, Javier; Carrasquilla, Gabriel; Rey, Luís; Dietze, Reynaldo; Giovanni Luz, Kléber; Rivas, Enrique; Consuelo Miranda, María; Cortés Supelano, Margarita; Zambrano, Betzana; Langevin, Edith; Boaz, Mark; Tornieporth, Nadia; Saville, Mélanie; Noriega, Fernando

doi:10.1056/nejmoa1411037

Public

Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

Published in New England Journal of Medicine • Nov 3, 2014

Authors:

Luis Villar

Gustavo H. Dayan

José Luis Arredondo-Garcı́a

Abstract

BACKGROUND: In light of the increasing rate of dengue infections throughout the world despite vector-control measures, several dengue vaccine candidates are in development. METHODS: In a phase 3 efficacy trial of a tetravalent dengue vaccine in five Latin American countries where dengue is endemic, ...

Subject

Medicine

Dengue fever

Dengue vaccine

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