Whole-Body Hypothermia for Neonates with Hypoxic–Ischemic Encephalopathy

Shankaran, Seetha; R. Laptook, Abbot; A. Ehrenkranz, Richard; E. Tyson, Jon; A. McDonald, Scott; F. Donovan, Edward; A. Fanaroff, Avroy; Kenneth Poole, W.; L. Wright, Linda; D. Higgins, Rosemary; N. Finer, Neil; A. Carlo, Waldemar; Duara, Shahnaz; Oh, William; Michael Cotten, C.; K. Stevenson, David; J. Stoll, Barbara; A. Lemons, James; Guillet, Ronnie; H. Jobe, Alan

doi:10.1056/nejmcps050929

Public

Whole-Body Hypothermia for Neonates with Hypoxic–Ischemic Encephalopathy

Published in New England Journal of Medicine • Oct 12, 2005

Authors:

Seetha Shankaran

Abbot R. Laptook

Richard A. Ehrenkranz

Abstract

BACKGROUND: Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain. METHODS: We conducted a randomized trial of hypothermia in infants with a gestational age of at least...

Subject

Medicine

Hypothermia

Encephalopathy

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