FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

Qi, Qibin; O. Kilpeläinen, Tuomas; K. Downer, Mary; Tanaka, Toshiko; E. Smith, Caren; Sluijs, Ivonne; Sonestedt, Emily; Y. Chu, Audrey; Renström, Frida; Lin, Xiaochen; Ängquist, Lars; Huang, Jinyan; Liu, Zhonghua; Li, Yanping; Asif Ali, Muhammad; Xu, Min; S. Ahluwalia, Tarunveer; M.A. Boer, Jolanda; Chen, Peng; Daimon, Makoto; G. Eriksson, Johan; Perola, Markus; Friedlander, Yechiel; Gao, Yu-Tang; H. M. Heppe, Denise; W. Holloway, John; K. Houston, Denise; Kanoni, Stavroula; Kim, Yu‐Mi; A. Laaksonen, Maarit; Jääskeläinen, Tiina; Lee, Sang; Lehtimäki, Terho; N. Lemaître, Rozenn; Lu, Wei; Luben, Robert; Manichaikul, Ani; Männistö, Satu; Marques‐Vidal, Pedro; L. Monda, Keri; S. Ngwa, Julius; Përusse, Louis; J.A. van Rooij, Frank; Xiang, Yong-Bing; Wen, Wanqing; K. Wojczynski, Mary; Zhu, Jingwen; B. Borecki, Ingrid; Bouchard, Claude; Cai, Qiuyin; Cooper, Cyrus; Dedoussis, George; Deloukas, Panos; Ferrucci, Luigi; G. Forouhi, Nita; Hansen, Torben; Christiansen, Lene; Hofman, Albert; Johansson, Ingegerd; Jørgensen, Torben; Karasawa, Shigeru; Khaw, Kay‐Tee; Kyung Kim, Mi; Kristiansson, Kati; Li, Huaixing; Xu, Lin; Liu, Ching‐Ti; K. Lohman, Kurt; Long, Jirong; Mikkilä, Vera; Mozaffarian, Dariush; E. North, Kari; Pedersen, Oluf; T. Raitakari, Olli; Rissanen, Harri; Tuomilehto, Jaakko; T. van der Schouw, Yvonne; G. Uitterlinden, André; Carola Zillikens, M.; H. Franco, Oscar; Shyong Tai, E; Ou Shu, Xiao; S. Siscovick, David; Toft, Ulla; M. Monique Verschuren, W.; Vollenweider, Péter; J. Wareham, Nicholas; C.M. Witteman, Jacqueline; Zheng, Wei; M. Ridker, Paul; Kang, Jae‐Heon; Liang, Liming; K. Jensen, Majken; C. Curhan, Gary; R. Pasquale, Louis; J. Hunter, David; L. Mohlke, Karen; Uusitupa, Matti; Adrienne Cupples, L.; Rankinen, Tuomo; Orho‐Melander, Marju; Wang, Tao; I. Chasman, Daniel; W. Franks, Paul; I. A. Sørensen, Thorkild; B. Hu, Frank; J. F. Loos, Ruth; A. Nettleton, Jennifer; Qi, Lu

doi:10.1093/hmg/ddu411

Public

FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

Published in Human Molecular Genetics • Aug 7, 2014

Authors:

Qibin Qi

Tuomas O. Kilpeläinen

Mary K. Downer

Abstract

FTO is the strongest known genetic susceptibility locus for obesity. Experimental studies in animals suggest the potential roles of FTO in regulating food intake. The interactive relation among FTO variants, dietary intake and body mass index (BMI) is complex and results from previous often small-sc...

Subject

Biology

Body mass index

Genetics

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