Vascular Effects of Apelin In Vivo in Man

G. Japp, Alan; L. Cruden, Nicholas; A.B. Amer, David; K.Y. Li, Vivienne; B. Goudie, Ewan; R. Johnston, Neil; Sharma, Sushma; Neilson, Ilene; J. Webb, David; L. Megson, Ian; D. Flapan, Andrew; E. Newby, David

doi:10.1016/j.jacc.2008.06.013

Public

Vascular Effects of Apelin In Vivo in Man

Published in Journal of the American College of Cardiology • Sep 1, 2008

Authors:

Alan G. Japp

Nicholas L. Cruden

David A.B. Amer

Abstract

OBJECTIVES: This study was designed to establish the direct vascular effects of apelin in vivo in man. BACKGROUND: Apelin is the endogenous ligand for the previously orphaned G-protein-coupled receptor, APJ. This novel pathway is widely expressed in the cardiovascular system and is emerging as an im...

Subject

Apelin

Sodium nitroprusside

Vasodilation

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