Copper chelation represses the vascular response to injury

Mandinov, Lazar; Mandinova, Anna; Kyurkchiev, Stanimir; Kyurkchiev, Dobroslav; Kehayov, Ivan; N. Kolev, Vihren; Soldi, Raffaella; Bagalá, Cinzia; D. de Muinck, Ebo; Lindner, Volkhard; J. Post, Mark; Simons, Michael; Bellum, Stephen; Prudovsky, Igor; Maciag, Thomas

doi:10.1073/pnas.1231994100

Public

Copper chelation represses the vascular response to injury

Published in Proceedings of the National Academy of Sciences • May 16, 2003

Authors:

Lazar Mandinov

Anna Mandinova

Stanimir Kyurkchiev

Abstract

The induction of an acute inflammatory response followed by the release of polypeptide cytokines and growth factors from peripheral blood monocytes has been implicated in mediating the response to vascular injury. Because the Cu2+-binding proteins IL-1alpha and fibroblast growth factor 1 are exporte...

Subject

Vascular smooth muscle

In vivo

Intracellular

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!