Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle

G. Le Roch, Karine; Zhou, Yingyao; L. Blair, Peter; Grainger, Muni; Kathleen Moch, J.; David Haynes, J.; De la Vega, Patricia; A. Holder, Anthony; Batalov, Serge; J. Carucci, Daniel; A. Winzeler, Elizabeth

doi:10.1126/science.1087025

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Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle

Shared by NobleBlocks on Sep 12, 2003 • 12:00 AM UTC

Authors:

Karine G. Le Roch

Yingyao Zhou

Peter L. Blair

Abstract

The completion of the genome sequence for Plasmodium falciparum , the species responsible for most malaria human deaths, has the potential to reveal hundreds of new drug targets and proteins involved in pathogenesis. However, only ∼35% of the genes code for proteins with an identifiable function. Th...

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