Toxicity Assessment of Cadinene Sesquiterpenes from Eupatorium adenophorum in Mice

Ouyang, Canbin; Liu, Xiaoman; Liu, Qi; Bai, Jie; Li, Hou-Yong; Li, Yuan; Wang, Qiuxia; Yan, Dongdong; Mao, Liangang; Cao, Aocheng; Guo, Meixia

doi:10.1007/s13659-014-0050-2

Public

Toxicity Assessment of Cadinene Sesquiterpenes from Eupatorium adenophorum in Mice

Published in Natural Products and Bioprospecting • Dec 11, 2014

Authors:

Canbin Ouyang

Xiaoman Liu

Qi Liu

Abstract

This study evaluated toxic efficacy of Eupatorium adenophorum extracts, against the Kunming mice. In acute study, we firstly tested median lethal dose (LD50) in mice of three cadinene sesquiterpenes 2-deoxo-2-(acetyloxy)-9-oxoageraphorone (DAOA), 9-oxo-agerophorone (OA) and 9-oxo-10,11-dehydro-agero...

Subject

Eupatorium

Acute toxicity

Toxicity

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